Using hypoallergenic materials is a high priority for Roche. Our infusion sets are latex- and PVC-free, and glues and solvents are used as little as possible. The adhesive tape is also specially designed to allow the skin underneath it to breathe. However, allergic reactions can never fully be ruled out. Sometimes they develop suddenly, even if you have used the same product for years. If an allergic reaction should occur, ask your physician about products that can help you continue a comfortable therapy.